human YAP1 Over-expression AAV

Name 
AAV-h-YAP1
Cat No 
AAV-227945
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human YAP1.

AAV-227945
AAV-h-YAP1

Ready-to-use AAV expressing Human YAP1 (Yes associated protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
65 kDa Yes-associated protein; COB1; protein yorkie homolog; transcriptional coactivator YAP1; YAP; YAP2; YAP65; yes-associated protein 1; yes-associated protein 2; yes-associated protein YAP65 homolog; YKI; yorkie homolog
Description (eCommerce)
Yes-associated protein 1 (YAP1) is the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. This protein contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction [taken from NCBI GeneID:10413].
Description (Vector)
YAP1 encodes the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. This protein contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction.
Gene ID
10413
Gene Name (eCommerce)
Yes associated protein 1
Gene Name (Vector)
Yes associated protein 1
Gene Symbol
YAP1
HGNC ID
HGNC:16262
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1515
ORF Size (bp)
1515 bp
Protein Name (eCommerce)
Transcriptional coactivator YAP1
RefSeq ID
NM_006106
RefSeq Synonyms
NM_006106, NM_001282101, NM_001282100, NM_001282099, NM_001282098, NM_001282097, NM_001195045, NM_001195044, NM_001130145, BC038235,
Research Areas
Apoptosis,Cancer,Cardiac Development,Cardiology,Cardiovascular,DNA Damage/Repair,Gene Expression,Hippo Signaling,Neurobiology,Neurodevelopment,RNA Binding,Signal Transduction,TGF-beta Signaling,Transcription Factor/Regulator,Wnt Signaling
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,developmental_biology,genetics,transcription_translation,immunology,neurobiology,signal_transduction
Species
human
Target Sentence
Yes-associated protein 1 (YAP1) is the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. This protein contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction [taken from NCBI GeneID:10413].
UniGene ID
Hs.503692
UniProt ID (eCommerce)
P46937

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.