human XYLT2 Over-expression AAV

Name 
AAV-h-XYLT2
Cat No 
AAV-227943
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human XYLT2.

AAV-227943
AAV-h-XYLT2

Ready-to-use AAV expressing Human XYLT2 (xylosyltransferase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PXYLT2; SOS; XT-II; XT2; xylT-II
Description (Vector)
XYLT2 is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.
Gene ID
64132
Gene Name (Vector)
xylosyltransferase 2
Gene Symbol
XYLT2
HGNC ID
HGNC:15517
ORF Size (aa)
2598
ORF Size (bp)
2598 bp
RefSeq ID
NM_022167
RefSeq Synonyms
NM_022167, BC156444, BC052262,
Species
human
UniGene ID
Hs.463416

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.