human WDR6 Over-expression AAV

Name 
AAV-h-WDR6
Cat No 
AAV-227701
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human WDR6.

AAV-227701
AAV-h-WDR6

Ready-to-use AAV expressing Human WDR6 (WD repeat domain 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
WD repeat-containing protein 6
Description (eCommerce)
WDR6 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest. Alternative splicing results in multiple transcript variants encoding different isoforms. [taken from NCBI Entrez Gene (Gene ID: 11180)].
Description (Vector)
WDR6 encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest.
Gene ID
11180
Gene Name (eCommerce)
WD repeat domain 6
Gene Name (Vector)
WD repeat domain 6
Gene Symbol
WDR6
HGNC ID
HGNC:12758
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3366
ORF Size (bp)
3366 bp
Protein Name (eCommerce)
WD repeat-containing protein 6
RefSeq ID
NM_018031
RefSeq Synonyms
NM_018031, NM_001320547, NM_001320546, BC113467, BC101707,
Research Areas
Autophagy,Cell Cycle
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
WDR6 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest. Alternative splicing results in multiple transcript variants encoding different isoforms. [taken from NCBI Entrez Gene (Gene ID: 11180)].
UniGene ID
Hs.654815
UniProt ID (eCommerce)
Q9NNW5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.