human WDR42A Over-expression AAV

Name 
AAV-h-WDR42A
Cat No 
AAV-227678
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DCAF8.

AAV-227678
AAV-h-WDR42A

Ready-to-use AAV expressing Human DCAF8 (DDB1 and CUL4 associated factor 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DDB1- and CUL4-associated factor 8; GAN2; H326; WD repeat domain 42A; WD repeat-containing protein 42A; WDR42A
Description (eCommerce)
WDR42A (WD repeat-containing protein 42A) contains seven WD repeats and is a member of the WD family of proteins. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. WD proteins are involved in a variety of cellular processes. The function of WDR42A has not been characterized.
Description (Vector)
DCAF8 encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular complex. Multiple alternatively spliced transcript variants have been found for this gene.
Gene ID
50717
Gene Name (eCommerce)
DDB1 and CUL4 associated factor 8
Gene Name (Vector)
DDB1 and CUL4 associated factor 8
Gene Symbol
DCAF8
HGNC ID
HGNC:24891
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1794
ORF Size (bp)
1794 bp
Protein Name (eCommerce)
DDB1- and CUL4-associated factor 8
RefSeq ID
NM_015726
RefSeq Synonyms
NM_015726, BC099846, BC099709, BC098271,
Research Areas
Cell Biology,Translational Control,Ubiquitination
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
WDR42A (WD repeat-containing protein 42A) contains seven WD repeats and is a member of the WD family of proteins. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. WD proteins are involved in a variety of cellular processes. The function of WDR42A has not been characterized.
UniGene ID
Hs.632447
UniProt ID (eCommerce)
Q5TAQ9

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.