human VRK3 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-227558
Availability:
3-5 weeks
Name:
AAV-h-VRK3
This is an AAV expressing Human VRK3.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- VRK3
- Gene Name
- vaccinia related kinase 3
- Gene ID
- 51231
- ORF Size
- 1239 bp
- RefSeq#
- BC023556
- Gene Description
- VRK3 encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. VRK3 is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms.
- UniGene ID
- Hs.443330
- HGNC ID
- HGNC:18996
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