human USP39 Over-expression AAV

Name 
AAV-h-USP39
Cat No 
AAV-227319
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human USP39.

AAV-227319
AAV-h-USP39

Ready-to-use AAV expressing Human USP39 (ubiquitin specific peptidase 39). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
65K; CGI-21; HSPC332; inactive ubiquitin-specific peptidase 39; SAD1; SAD1 homolog; small nuclear ribonucleoprotein 65kDa (U4/U6.U5); SnRNP assembly defective 1 homolog; SNRNP65; U4/U6.U5 tri-snRNP-associated 65 kDa protein; U4/U6.U5 tri-snRNP-associated protein 2; ubiquitin specific protease 39
Description (eCommerce)
USP39 plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. USP39 regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. USP39 does not have ubiquitin-specific peptidase activity, but could be a competitor of ubiquitin C-terminal hydrolases (UCHs) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q53GS9].
Gene ID
10713
Gene Name (eCommerce)
ubiquitin specific peptidase 39
Gene Name (Vector)
ubiquitin specific peptidase 39
Gene Symbol
USP39
HGNC ID
HGNC:20071
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1698
ORF Size (bp)
1698 bp
Protein Name (eCommerce)
U4/U6.U5 tri-snRNP-associated protein 2
RefSeq ID
NM_006590
RefSeq Synonyms
NM_006590, NM_001256728, NM_001256727, NM_001256726, NM_001256725, BC067273,
Research Areas
Cell Cycle,Cell Division,Gene Expression,mRNA Processing,mRNA Splicing,RNA Processing,Spliceosome,Zinc-finger
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
USP39 plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. USP39 regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. USP39 does not have ubiquitin-specific peptidase activity, but could be a competitor of ubiquitin C-terminal hydrolases (UCHs) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q53GS9].
UniGene ID
Hs.654745
UniProt ID (eCommerce)
Q53GS9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.