human UPB1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-227221
Availability:
3-5 weeks
Name:
AAV-h-UPB1
This is an AAV expressing Human UPB1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- UPB1
- Gene Name
- beta-ureidopropionase 1
- Gene ID
- 51733
- Gene Synonyms
- BUP1
- ORF Size
- 1155 bp
- RefSeq#
- BC139840
- Gene Description
- UPB1 encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.
- UniGene ID
- Hs.474388
- HGNC ID
- HGNC:16297
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