human UNG Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-227212
Availability:
3-5 weeks
Name:
AAV-h-UNG
This is an AAV expressing Human UNG.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- UNG
- Gene Name
- uracil DNA glycosylase
- Gene ID
- 7374
- Gene Synonyms
- DGU; HIGM4; HIGM5; UDG; UNG1; UNG15; UNG2
- ORF Size
- 915 bp
- RefSeq#
- BC015205
- Gene Description
- UNG encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.
- UniGene ID
- Hs.191334
- HGNC ID
- HGNC:12572
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