human UBR7 Over-expression AAV

Name 
AAV-h-UBR7
Cat No 
AAV-227083
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human UBR7.

AAV-227083
AAV-h-UBR7

Ready-to-use AAV expressing Human UBR7 (ubiquitin protein ligase E3 component n-recognin 7 (putative)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C14orf130; N-recognin-7; putative E3 ubiquitin-protein ligase UBR7; RING-type E3 ubiquitin transferase UBR7
Description (eCommerce)
Putative E3 ubiquitin-protein ligase UBR7 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. UBR7 recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8N806].
Gene ID
55148
Gene Name (eCommerce)
ubiquitin protein ligase E3 component n-recognin 7 (putative)
Gene Name (Vector)
ubiquitin protein ligase E3 component n-recognin 7 (putative)
Gene Symbol
UBR7
HGNC ID
HGNC:20344
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1086
ORF Size (bp)
1086 bp
Protein Name (eCommerce)
Putative E3 ubiquitin-protein ligase UBR7
RefSeq ID
NM_175748
RefSeq Synonyms
NM_175748, BC051819, BC017013, BC015046,
Research Areas
Ubiquitination,Zinc-finger
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Putative E3 ubiquitin-protein ligase UBR7 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. UBR7 recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8N806].
UniGene ID
Hs.648806
UniProt ID (eCommerce)
Q8N806

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.