human UBA7 Over-expression AAV

Name 
AAV-h-UBA7
Cat No 
AAV-226968
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human UBA7.

AAV-226968
AAV-h-UBA7

Ready-to-use AAV expressing Human UBA7 (ubiquitin like modifier activating enzyme 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
D8; UBA1B; UBE1L; UBE2
Description (Vector)
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.
Gene ID
7318
Gene Name (Vector)
ubiquitin like modifier activating enzyme 7
Gene Symbol
UBA7
HGNC ID
HGNC:12471
ORF Size (aa)
3039
ORF Size (bp)
3039 bp
RefSeq ID
NM_003335
RefSeq Synonyms
NM_003335, BC006378,
Species
human
UniGene ID
Hs.16695

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.