human TXNDC12 Over-expression AAV

Name 
AAV-h-TXNDC12
Cat No 
AAV-226899
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TXNDC12.

AAV-226899
AAV-h-TXNDC12

Ready-to-use AAV expressing Human TXNDC12 (thioredoxin domain containing 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AG1; AGR1; ERP16; ERP18; ERP19; hAG-1; hTLP19; PDIA16; TLP19
Description (Vector)
TXNDC12 encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants.
Gene ID
51060
Gene Name (Vector)
thioredoxin domain containing 12
Gene Symbol
TXNDC12
HGNC ID
HGNC:24626
ORF Size (aa)
519
RefSeq ID
NM_015913
RefSeq Synonyms
NM_015913, BC008953, BC008913, BC001493,
Species
human
UniGene ID
Hs.476033

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.