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human TSEN54 Over-expression AAV

Name 
AAV-h-TSEN54
Cat No 
AAV-226594
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TSEN54.

AAV-226594
AAV-h-TSEN54

Ready-to-use AAV expressing Human TSEN54 (tRNA splicing endonuclease subunit 54). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PCH2A; PCH4; PCH5; sen54; SEN54L
Description (Vector)
TSEN54 encodes a subunit of the tRNA splicing endonuclease complex, which catalyzes the removal of introns from precursor tRNAs. The complex is also implicated in pre-mRNA 3-prime end processing. Mutations in this gene result in pontocerebellar hypoplasia type 2.
Gene ID
283989
Gene Name (Vector)
tRNA splicing endonuclease subunit 54
Gene Symbol
TSEN54
HGNC ID
HGNC:27561
ORF Size (aa)
1581
ORF Size (bp)
1581 bp
RefSeq ID
NM_207346
RefSeq Synonyms
NM_207346, BC047793,
Species
human
UniGene ID
Hs.655875

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.