human TRPM5 Over-expression AAV

Name 
AAV-h-TRPM5
Cat No 
AAV-226555
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TRPM5.

AAV-226555
AAV-h-TRPM5

Ready-to-use AAV expressing Human TRPM5 (transient receptor potential cation channel subfamily M member 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
LTRPC5; MTR1
Description (Vector)
TRPM5 encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. TRPM5 is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele.
Gene ID
29850
Gene Name (Vector)
transient receptor potential cation channel subfamily M member 5
Gene Symbol
TRPM5
HGNC ID
HGNC:14323
ORF Size (aa)
3498
ORF Size (bp)
3498 bp
RefSeq ID
NM_014555
RefSeq Synonyms
NM_014555, BC143353, BC143351, BC093789, BC093787,
Species
human
UniGene ID
Hs.272287

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.