human TNNT2 Over-expression AAV

Name 
AAV-h-TNNT2
Cat No 
AAV-226142
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TNNT2.

AAV-226142
AAV-h-TNNT2

Ready-to-use AAV expressing Human TNNT2 (troponin T2, cardiac type). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TnTC
Description (Vector)
TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
Gene ID
7139
Gene Name (Vector)
troponin T2, cardiac type
Gene Symbol
TNNT2
HGNC ID
HGNC:11949
ORF Size (aa)
858
RefSeq ID
NM_000364
RefSeq Synonyms
NM_001276347, NM_001276346, NM_001276345, NM_001001432, NM_001001431, NM_001001430, NM_000364, BC002653,
Species
human
UniGene ID
Hs.533613

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.