human TNFAIP3 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-226059
Availability:
3-5 weeks
Name:
AAV-h-TNFAIP3
This is an AAV expressing Human TNFAIP3.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- TNFAIP3
- Gene Name
- TNF alpha induced protein 3
- Gene ID
- 7128
- Gene Synonyms
- A20; AISBL; OTUD7C; TNFA1P2
- ORF Size
- 2373 bp
- RefSeq#
- BC113871
- Gene Description
- TNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.
- UniGene ID
- Hs.211600
- HGNC ID
- HGNC:11896
Related Products
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