human TMEM195 Over-expression AAV

Name 
AAV-h-TMEM195
Cat No 
AAV-225833
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human AGMO.

AAV-225833
AAV-h-TMEM195

Ready-to-use AAV expressing Human AGMO (alkylglycerol monooxygenase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
TMEM195
Description (Vector)
AGMO is a tetrahydrobiopterin- and iron-dependent enzyme that cleaves the ether bond of alkylglycerols. Sequence comparisons distinguish this protein as forming a third, distinct class of tetrahydrobiopterin-dependent enzymes. Variations in this gene have been associated with decreased glucose-stimulated insulin response, type 2 diabetes, and susceptibility to intracranial aneurysms.
Gene ID
392636
Gene Name (Vector)
alkylglycerol monooxygenase
Gene Symbol
AGMO
HGNC ID
HGNC:33784
ORF Size (aa)
1338
ORF Size (bp)
1338 bp
RefSeq ID
NM_001004320
RefSeq Synonyms
NM_001004320, BC108676,
Species
human
UniGene ID
Hs.670634

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.