human TMEM195 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-225833
Availability:
3-5 weeks
Name:
AAV-h-TMEM195
This is an AAV expressing Human AGMO.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- AGMO
- Gene Name
- alkylglycerol monooxygenase
- Gene ID
- 392636
- Gene Synonyms
- TMEM195
- ORF Size
- 1338 bp
- RefSeq#
- BC108676
- Gene Description
- AGMO is a tetrahydrobiopterin- and iron-dependent enzyme that cleaves the ether bond of alkylglycerols. Sequence comparisons distinguish this protein as forming a third, distinct class of tetrahydrobiopterin-dependent enzymes. Variations in this gene have been associated with decreased glucose-stimulated insulin response, type 2 diabetes, and susceptibility to intracranial aneurysms.
- UniGene ID
- Hs.670634
- HGNC ID
- HGNC:33784
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