human TMC1 Over-expression AAV

Name
AAV-h-TMC1

Cat No
AAV-225646

Availability
4-5 weeks

This is an AAV expressing Human TMC1.

AAV-225646

AAV-h-TMC1

Ready-to-use AAV expressing Human TMC1 (transmembrane channel like 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DFNA36; DFNB11; DFNB7

Description (Vector)

TMC1 is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown; however, it is known to be required for normal function of cochlear hair cells. Mutations in this gene have been associated with progressive postlingual hearing loss and profound prelingual deafness.

Gene ID

117531

Gene Name (Vector)

transmembrane channel like 1

Gene Symbol

TMC1

HGNC ID

HGNC:16513

ORF Size (aa)

2283

ORF Size (bp)

2283 bp

RefSeq ID

NM_138691

RefSeq Synonyms

NM_138691, BC172523, BC156561,

Species

human

UniGene ID

Hs.670211

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.