human TMC1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TMC1.
shAAV-225647
AAV-h-TMC1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TMC1 (transmembrane channel like 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DFNA36; DFNB11; DFNB7
Description (Vector)
TMC1 is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown; however, it is known to be required for normal function of cochlear hair cells. Mutations in this gene have been associated with progressive postlingual hearing loss and profound prelingual deafness.
Gene ID
117531
Gene Name (Vector)
transmembrane channel like 1
Gene Symbol
TMC1
HGNC ID
HGNC:16513
ORF Size (aa)
2283
ORF Size (bp)
2283 bp
RefSeq ID
NM_138691
RefSeq Synonyms
NM_138691, BC172523, BC156561,
Species
human
UniGene ID
Hs.670211
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.