human TICAM1 Over-expression AAV

Name 
AAV-h-TICAM1
Cat No 
AAV-225491
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TICAM1.

AAV-225491
AAV-h-TICAM1

Ready-to-use AAV expressing Human TICAM1 (toll like receptor adaptor molecule 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IIAE6; MyD88-3; PRVTIRB; TICAM-1; TRIF
Description (Vector)
TICAM1 encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.
Gene ID
148022
Gene Name (Vector)
toll like receptor adaptor molecule 1
Gene Symbol
TICAM1
HGNC ID
HGNC:18348
ORF Size (aa)
2139
ORF Size (bp)
2139 bp
RefSeq ID
NM_182919
RefSeq Synonyms
NM_182919, BC136557, BC136556, BC035331,
Species
human
UniGene ID
Hs.29344

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.