human THEM4 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-225440
Availability:
3-5 weeks
Name:
AAV-h-THEM4
This is an AAV expressing Human THEM4.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- THEM4
- Gene Name
- thioesterase superfamily member 4
- Gene ID
- 117145
- Gene Synonyms
- CTMP
- ORF Size
- 723 bp
- RefSeq#
- BC065277
- Gene Description
- Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas.
- UniGene ID
- Hs.164070
- HGNC ID
- HGNC:17947
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