human TGM1 Over-expression AAV

Name 
AAV-h-TGM1
Cat No 
AAV-225400
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TGM1.

AAV-225400
AAV-h-TGM1

Ready-to-use AAV expressing Human TGM1 (transglutaminase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ARCI1; ICR2; KTG; LI; LI1; TGASE; TGK
Description (Vector)
TGM1 is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE).
Gene ID
7051
Gene Name (Vector)
transglutaminase 1
Gene Symbol
TGM1
HGNC ID
HGNC:11777
ORF Size (aa)
2454
ORF Size (bp)
2454 bp
RefSeq ID
NM_000359
RefSeq Synonyms
NM_000359, BC034699,
Species
human
UniGene ID
Hs.508950

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.