human TBR1 Over-expression AAV

Name
AAV-h-TBR1

Cat No
AAV-225145

Availability
4-5 weeks

This is an AAV expressing Human TBR1.

AAV-225145

AAV-h-TBR1

Ready-to-use AAV expressing Human TBR1 (T-box, brain 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

TBR-1; TES-56

Description (Vector)

TBR1 is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.

Gene ID

10716

Gene Name (Vector)

T-box, brain 1

Gene Symbol

TBR1

HGNC ID

HGNC:11590

ORF Size (aa)

2049

ORF Size (bp)

2049 bp

RefSeq ID

NM_006593

RefSeq Synonyms

NM_006593, BC113418, BC104844,

Species

human

UniGene ID

Hs.210862

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.