human TAF8 Over-expression AAV

Name 
AAV-h-TAF8
Cat No 
AAV-224931
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TAF8.

AAV-224931
AAV-h-TAF8

Ready-to-use AAV expressing Human TAF8 (TATA-box binding protein associated factor 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
hTAFII43; II; protein taube nuss; TAF; TAF(II)43; TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa; TAFII43; TAFII-43; TATA box binding protein (TBP)-associated factor, RNA polymerase II, A, 45/50kDa; taube nuss homolog; TBN; TBP-associated factor 43 kDa; TBP-associated factor 8; TBP-associated factor TAFII43; TBP-associated factor, RNA polymerase II, 43 kD; transcription initiation factor TFIID 43 kDa subunit; transcription initiation factor TFIID subunit 8
Description (eCommerce)
Transcription initiation factor TFIID subunit 8 is one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. TAF8 contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10 [taken from NCBI Entrez Gene (Gene ID: 129685)].
Description (Vector)
TAF8 encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Gene ID
129685
Gene Name (eCommerce)
TATA-box binding protein associated factor 8
Gene Name (Vector)
TATA-box binding protein associated factor 8
Gene Symbol
TAF8
HGNC ID
HGNC:17300
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
936
Protein Name (eCommerce)
Transcription initiation factor TFIID subunit 8
RefSeq ID
NM_138572
RefSeq Synonyms
NM_138572, BC119679, BC119678, BC033728,
Research Areas
Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Transcription initiation factor TFIID subunit 8 is one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. TAF8 contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10 [taken from NCBI Entrez Gene (Gene ID: 129685)].
UniGene ID
Hs.520122
UniProt ID (eCommerce)
Q7Z7C8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.