human SRM Over-expression AAV

Name 
AAV-h-SRM
Cat No 
AAV-224333
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SRM.

AAV-224333
AAV-h-SRM

Ready-to-use AAV expressing Human SRM (spermidine synthase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PAPT; putrescine aminopropyltransferase; SPDSY; spermidine synthase; spermidine synthase-1; SPS1; SRML1
Description (eCommerce)
The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase (SRM) is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. Spermidine synthase catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor [taken from NCBI Entrez Gene (Gene ID: 6723)].
Description (Vector)
The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor.
Gene ID
6723
Gene Name (eCommerce)
spermidine synthase
Gene Name (Vector)
spermidine synthase
Gene Symbol
SRM
HGNC ID
HGNC:11296
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
909
Protein Name (eCommerce)
Spermidine synthase
RefSeq ID
NM_003132
RefSeq Synonyms
NM_003132, BC033106, BC000309,
Research Areas
Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase (SRM) is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. Spermidine synthase catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor [taken from NCBI Entrez Gene (Gene ID: 6723)].
UniGene ID
Hs.76244
UniProt ID (eCommerce)
P19623

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.