human SPPL2A Over-expression AAV

Name 
AAV-h-SPPL2A
Cat No 
AAV-224235
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SPPL2A.

AAV-224235
AAV-h-SPPL2A

Ready-to-use AAV expressing Human SPPL2A (signal peptide peptidase like 2A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IMP3; PSL2
Description (Vector)
SPPL2A encodes a member of the GXGD family of aspartic proteases, which are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions, as well as a member of the signal peptide peptidase-like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15.
Gene ID
84888
Gene Name (Vector)
signal peptide peptidase like 2A
Gene Symbol
SPPL2A
HGNC ID
HGNC:30227
ORF Size (aa)
1563
ORF Size (bp)
1563 bp
RefSeq ID
NM_032802
RefSeq Synonyms
NM_032802, BC025740,
Species
human
UniGene ID
Hs.401537

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.