human SNUPN Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-223909
Availability:
3-5 weeks
Name:
AAV-h-SNUPN
This is an AAV expressing Human SNUPN.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- SNUPN
- Gene Name
- snurportin 1
- Gene ID
- 10073
- Gene Synonyms
- KPNBL; RNUT1; Snurportin1
- ORF Size
- 1083 bp
- RefSeq#
- BC004203
- Gene Description
- The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
- UniGene ID
- Hs.21577
- HGNC ID
- HGNC:14245
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