human SMAD5 Over-expression AAV

Name 
AAV-h-SMAD5
Cat No 
AAV-223693
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SMAD5.

AAV-223693
AAV-h-SMAD5

Ready-to-use AAV expressing Human SMAD5 (SMAD family member 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DWFC; JV5-1; MADH5
Description (Vector)
SMAD5 is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by BMP type 1 receptor kinase. Three transcript variants encoding the same protein have been found for this gene.
Gene ID
4090
Gene Name (Vector)
SMAD family member 5
Gene Symbol
SMAD5
HGNC ID
HGNC:6771
ORF Size (aa)
1398
ORF Size (bp)
1398 bp
RefSeq ID
NM_001001419
RefSeq Synonyms
NM_005903, NM_001001420, NM_001001419, BC009682,
Species
human
UniGene ID
Hs.167700

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.