human GGA3 Over-expression AAV

Name
AAV-h-GGA3

Cat No
AAV-209839

Availability
4-5 weeks

This is an AAV expressing Human GGA3.

AAV-209839

AAV-h-GGA3

Ready-to-use AAV expressing Human GGA3 (golgi associated, gamma adaptin ear containing, ARF binding protein 3). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

GGA3 encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants have been identified in this gene.

Gene ID

23163

Gene Name (Vector)

golgi associated, gamma adaptin ear containing, ARF binding protein 3

Gene Symbol

GGA3

HGNC ID

HGNC:17079

ORF Size (aa)

2073

ORF Size (bp)

2073 bp

RefSeq ID

NM_014001

RefSeq Synonyms

NM_138619, NM_014001, NM_001291642, NM_001291641, NM_001172704, NM_001172703, BC070044,

Species

human

UniGene ID

Hs.87726

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.