human SLC7A11 Over-expression AAV

Name 
AAV-h-SLC7A11
Cat No 
AAV-223586
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SLC7A11.

AAV-223586
AAV-h-SLC7A11

Ready-to-use AAV expressing Human SLC7A11 (solute carrier family 7 member 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CCBR1; xCT
Description (Vector)
SLC7A11 encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.
Gene ID
23657
Gene Name (Vector)
solute carrier family 7 member 11
Gene Symbol
SLC7A11
HGNC ID
HGNC:11059
ORF Size (aa)
1506
ORF Size (bp)
1506 bp
RefSeq ID
NM_014331
RefSeq Synonyms
NM_014331, BC012087,
Species
human
UniGene ID
Hs.390594

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.