human SKI Over-expression AAV

Name 
AAV-h-SKI
Cat No 
AAV-223042
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SKI.

AAV-223042
AAV-h-SKI

Ready-to-use AAV expressing Human SKI (SKI proto-oncogene). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
proto-oncogene c-Ski; SGS; ski oncogene; ski oncoprotein; SKV; v-ski avian sarcoma viral oncogene homolog
Description (eCommerce)
c-Ski is the nuclear proto-oncogene protein homolog of avian sarcoma viral (v-ski) oncogene. It functions as a repressor of TGF-beta signaling, and may play a role in neural tube development and muscle differentiation.
Description (Vector)
SKI encodes the nuclear protooncogene protein homolog of avian sarcoma viral (v-ski) oncogene. It functions as a repressor of TGF-beta signaling, and may play a role in neural tube development and muscle differentiation.
Gene ID
6497
Gene Name (eCommerce)
SKI proto-oncogene
Gene Name (Vector)
SKI proto-oncogene
Gene Symbol
SKI
HGNC ID
HGNC:10896
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2184
ORF Size (bp)
2184 bp
Protein Name (eCommerce)
Ski oncogene
RefSeq ID
NM_003036
RefSeq Synonyms
NM_003036, BC157082, BC156044,
Research Areas
Apoptosis,Cancer,Chromatin Remodeling,Gene Expression,Neurobiology,Neurodevelopment,Notch Signaling,Signal Transduction,TGF-beta Signaling,Transcription Factor/Regulator,Tumor Suppressors/Oncoproteins,Ubiquitination,Wnt Signaling
Research Areas (Faceted)
cancer,signal_transduction,cell_biology,genetics,transcription_translation,neurobiology,developmental_biology,developmental_biology,signal_transduction,immunology,genetics,transcription_translation,cancer,genetics,signal_transduction,developmental_biology
Species
human
Target Sentence
c-Ski is the nuclear proto-oncogene protein homolog of avian sarcoma viral (v-ski) oncogene. It functions as a repressor of TGF-beta signaling, and may play a role in neural tube development and muscle differentiation.
UniGene ID
Hs.663133
UniProt ID (eCommerce)
P12755

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.