human SIL1 Over-expression AAV

Name 
AAV-h-SIL1
Cat No 
AAV-223001
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SIL1.

AAV-223001
AAV-h-SIL1

Ready-to-use AAV expressing Human SIL1 (SIL1 nucleotide exchange factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BAP; MSS; ULG5
Description (Vector)
SIL1 encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.
Gene ID
64374
Gene Name (Vector)
SIL1 nucleotide exchange factor
Gene Symbol
SIL1
HGNC ID
HGNC:24624
ORF Size (aa)
1386
ORF Size (bp)
1386 bp
RefSeq ID
NM_022464
RefSeq Synonyms
NM_022464, NM_001037633, BC011568,
Species
human
UniGene ID
Hs.483521

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.