human SGMS2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-222861
Availability:
3-5 weeks
Name:
AAV-h-SGMS2
This is an AAV expressing Human SGMS2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- SGMS2
- Gene Name
- sphingomyelin synthase 2
- Gene ID
- 166929
- Gene Synonyms
- SMS2
- ORF Size
- 1098 bp
- RefSeq#
- BC028705
- Gene Description
- Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. The protein encoded by this gene is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. The encoded protein is required for cell growth. Three transcript variants encoding the same protein have been found for this gene. There is evidence for more variants, but the full-length nature of their transcripts has not been determined.
- UniGene ID
- Hs.595423
- HGNC ID
- HGNC:28395
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