human SGCB Over-expression AAV

Name 
AAV-h-SGCB
Cat No 
AAV-222841
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SGCB.

AAV-222841
AAV-h-SGCB

Ready-to-use AAV expressing Human SGCB (sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A3b; LGMD2E; SGC
Description (Vector)
SGCB encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.
Gene ID
6443
Gene Name (Vector)
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
Gene Symbol
SGCB
HGNC ID
HGNC:10806
ORF Size (aa)
957
RefSeq ID
NM_000232
RefSeq Synonyms
NM_000232, BC020709,
Species
human
UniGene ID
Hs.438953

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.