human SGCA Over-expression AAV

Name 
AAV-h-SGCA
Cat No 
AAV-222840
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SGCA.

AAV-222840
AAV-h-SGCA

Ready-to-use AAV expressing Human SGCA (sarcoglycan alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
50DAG; adhalin; ADL; DAG2; DMDA2; LGMD2D; SCARMD1
Description (Vector)
SGCA encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
6442
Gene Name (Vector)
sarcoglycan alpha
Gene Symbol
SGCA
HGNC ID
HGNC:10805
ORF Size (aa)
1164
ORF Size (bp)
1164 bp
RefSeq ID
NM_000023
RefSeq Synonyms
NM_001135697, NM_000023, BC025702,
Species
human
UniGene ID
Hs.463412

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.