human SDHD Over-expression AAV
This is an AAV expressing Human SDHD.
AAV-222439
AAV-h-SDHD
Ready-to-use AAV expressing Human SDHD (succinate dehydrogenase complex subunit D). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CBT1; CII-4; CWS3; cybS; PGL; PGL1; QPs3; SDH4
Description (Vector)
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The subunit D protein is one of two integral membrane proteins anchoring the complex to the matrix side of the membrane. Mutations in SDHD have been linked to hereditary paraganglioma.
Gene ID
6392
Gene Name (Vector)
succinate dehydrogenase complex subunit D
Gene Symbol
SDHD
HGNC ID
HGNC:10683
ORF Size (aa)
480
ORF Size (bp)
480 bp
RefSeq ID
NM_003002
RefSeq Synonyms
NM_003002, NM_001276506, NM_001276504, NM_001276503, BC071756, BC071755, BC070307, BC022350, BC015992, BC015188, BC012603, BC009574, BC005263,
Species
human
UniGene ID
Hs.356270
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.