human SCYL2 Over-expression AAV

Name 
AAV-h-SCYL2
Cat No 
AAV-222407
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SCYL2.

AAV-222407
AAV-h-SCYL2

Ready-to-use AAV expressing Human SCYL2 (SCY1 like pseudokinase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
coated vesicle-associated kinase of 104 kDa; CVAK104; SCY1-like 2; SCY1-like protein 2; SCY1-like, kinase-like 2
Description (eCommerce)
SCY1-like protein 2 (SCYL2) is a component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. According to PubMed:15809293, it is a probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine. According to PubMed:16914521, it has no detectable kinase activity in vitro. SCYL2 may regulate clathrin-dependent trafficking between the TGN and/or the endosomal system [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6P3W7].
Gene ID
55681
Gene Name (eCommerce)
SCY1 like pseudokinase 2
Gene Name (Vector)
SCY1 like pseudokinase 2
Gene Symbol
SCYL2
HGNC ID
HGNC:19286
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2790
ORF Size (bp)
2790 bp
Protein Name (eCommerce)
SCY1-like protein 2
RefSeq ID
NM_017988
RefSeq Synonyms
NM_017988, NM_001330256, NM_001330254, NM_001330253, NM_001317784, BC063798,
Research Areas
Golgi Apparatus,Kinase/Phosphatase,Lysosomal Transport,Signal Transduction,Wnt Signaling
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
SCY1-like protein 2 (SCYL2) is a component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. According to PubMed:15809293, it is a probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine. According to PubMed:16914521, it has no detectable kinase activity in vitro. SCYL2 may regulate clathrin-dependent trafficking between the TGN and/or the endosomal system [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6P3W7].
UniGene ID
Hs.506481
UniProt ID (eCommerce)
Q6P3W7

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.