human SAA1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-222192
Availability:
3-5 weeks
Name:
AAV-h-SAA1
This is an AAV expressing Human SAA1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- SAA1
- Gene Name
- serum amyloid A1
- Gene ID
- 6288
- Gene Synonyms
- PIG4; SAA; SAA2; TP53I4
- ORF Size
- 369 bp
- RefSeq#
- BC007022
- Gene Description
- SAA1 encodes a member of the serum amyloid A family of apolipoproteins. The encoded protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.
- UniGene ID
- Hs.632144
- HGNC ID
- HGNC:10513
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