human RORA Over-expression AAV

Name 
AAV-h-RORA
Cat No 
AAV-221492
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RORA.

AAV-221492
AAV-h-RORA

Ready-to-use AAV expressing Human RORA (RAR related orphan receptor A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
NR1F1; ROR1; ROR2; ROR3; RZR-ALPHA; RZRA
Description (Vector)
RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.
Gene ID
6095
Gene Name (Vector)
RAR related orphan receptor A
Gene Symbol
RORA
HGNC ID
HGNC:10258
ORF Size (aa)
1407
ORF Size (bp)
1407 bp
RefSeq ID
NM_002943
RefSeq Synonyms
NM_134262, NM_134261, NM_134260, NM_002943, BC100990, BC100989, BC100988, BC100987, BC008831,
Species
human
UniGene ID
Hs.655155

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.