human RNF25 Over-expression AAV

Name 
AAV-h-RNF25
Cat No 
AAV-221420
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RNF25.

AAV-221420
AAV-h-RNF25

Ready-to-use AAV expressing Human RNF25 (ring finger protein 25). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AO7; E3 ubiquitin-protein ligase RNF25; RING finger protein 25; ring finger protein AO7; RING-type E3 ubiquitin transferase RNF25
Description (eCommerce)
RNF25 (RING finger protein 25) is an E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NKD2 (by similarity). RNF25 stimulates transcription mediated by NF-kappa-B [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96BH1].
Description (Vector)
RNF25 contains a RING finger motif. The mouse counterpart of this protein has been shown to interact with Rela, the p65 subunit of NF-kappaB (NFKB), and modulate NFKB-mediated transcription activity. The mouse protein also binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination.
Gene ID
64320
Gene Name (eCommerce)
ring finger protein 25
Gene Name (Vector)
ring finger protein 25
Gene Symbol
RNF25
HGNC ID
HGNC:14662
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1380
ORF Size (bp)
1380 bp
Protein Name (eCommerce)
E3 ubiquitin-protein ligase RNF25
RefSeq ID
NM_022453
RefSeq Synonyms
NM_022453, BC015612,
Research Areas
Antigen Processing and Presentation,Immunology,Signal Transduction,TNF Signaling,Transcription Factor/Regulator,Ubiquitination,Zinc-finger
Research Areas (Faceted)
cell_biology,immunology,signal_transduction,transcription_translation
Species
human
Target Sentence
RNF25 (RING finger protein 25) is an E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NKD2 (by similarity). RNF25 stimulates transcription mediated by NF-kappa-B [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96BH1].
UniGene ID
Hs.471403
UniProt ID (eCommerce)
Q96BH1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.