human SIKE1 Over-expression AAV

Name
AAV-h-SIKE1

Cat No
AAV-221525

Availability
4-5 weeks

This is an AAV expressing Human SIKE1.

AAV-221525

AAV-h-SIKE1

Ready-to-use AAV expressing Human SIKE1 (suppressor of IKBKE 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

SIKE

Description (Vector)

SIKE interacts with IKK-epsilon (IKBKE; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 (PubMed 16281057)).(supplied by OMIM, Mar 2008)

Gene ID

80143

Gene Name (Vector)

suppressor of IKBKE 1

Gene Symbol

SIKE1

HGNC ID

HGNC:26119

ORF Size (aa)

624

RefSeq ID

NM_025073

RefSeq Synonyms

NM_025073, NM_001102396, BC005934,

Species

human

UniGene ID

Hs.709277

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.