human RGS6 Over-expression AAV

Name 
AAV-h-RGS6
Cat No 
AAV-221131
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RGS6.

AAV-221131
AAV-h-RGS6

Ready-to-use AAV expressing Human RGS6 (regulator of G-protein signaling 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GAP; HA117; S914
Description (Vector)
RGS6 encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.
Gene ID
9628
Gene Name (Vector)
regulator of G-protein signaling 6
Gene Symbol
RGS6
HGNC ID
HGNC:10002
ORF Size (aa)
1419
ORF Size (bp)
1419 bp
RefSeq ID
NM_004296
RefSeq Synonyms
NM_004296, NM_001204424, NM_001204423, NM_001204422, NM_001204421, NM_001204420, NM_001204419, NM_001204418, NM_001204417, NM_001204416, BC113572, BC104877,
Species
human
UniGene ID
Hs.509872

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.