human RGS5 Over-expression AAV

Name 
AAV-h-RGS5
Cat No 
AAV-221130
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RGS5.

AAV-221130
AAV-h-RGS5

Ready-to-use AAV expressing Human RGS5 (regulator of G-protein signaling 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MST092; MST106; MST129; MSTP032; MSTP092; MSTP106; MSTP129
Description (Vector)
RGS5 encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. RGS5 is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. RGS5 is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified.
Gene ID
8490
Gene Name (Vector)
regulator of G-protein signaling 5
Gene Symbol
RGS5
HGNC ID
HGNC:10001
ORF Size (aa)
546
RefSeq ID
NM_003617
RefSeq Synonyms
NM_003617, NM_001254749, NM_001254748, NM_001195303, BC030059,
Species
human
UniGene ID
Hs.24950

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.