human RFWD3 Over-expression AAV

Name 
AAV-h-RFWD3
Cat No 
AAV-221065
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RFWD3.

AAV-221065
AAV-h-RFWD3

Ready-to-use AAV expressing Human RFWD3 (ring finger and WD repeat domain 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
E3 ubiquitin-protein ligase RFWD3; FANCW; RING finger and WD repeat domain-containing protein 3; RING finger protein 201; RING-type E3 ubiquitin transferase RFWD3; RNF201
Description (eCommerce)
RFWD3 (ring finger and WD repeat domain 3) has been identified as a protein that is phosphorylated in response to DNA damage. The exact function of RFWD3 (ring finger and WD repeat domain 3) has not been characterized. Structurally, RFWD3 possesses a RING-type zinc finger and 3 WD repeats.
Gene ID
55159
Gene Name (eCommerce)
ring finger and WD repeat domain 3
Gene Name (Vector)
ring finger and WD repeat domain 3
Gene Symbol
RFWD3
HGNC ID
HGNC:25539
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2325
ORF Size (bp)
2325 bp
Protein Name (eCommerce)
E3 ubiquitin-protein ligase RFWD3
RefSeq ID
NM_018124
RefSeq Synonyms
NM_018124, BC059371,
Research Areas
Cell Cycle,DNA Damage/Repair,Zinc-finger
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
RFWD3 (ring finger and WD repeat domain 3) has been identified as a protein that is phosphorylated in response to DNA damage. The exact function of RFWD3 (ring finger and WD repeat domain 3) has not been characterized. Structurally, RFWD3 possesses a RING-type zinc finger and 3 WD repeats.
UniGene ID
Hs.567525
UniProt ID (eCommerce)
Q6PCD5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.