human REXO2 Over-expression AAV

Name 
AAV-h-REXO2
Cat No 
AAV-221029
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human REXO2.

AAV-221029
AAV-h-REXO2

Ready-to-use AAV expressing Human REXO2 (RNA exonuclease 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CGI-114; oligoribonuclease, mitochondrial; REX2; REX2, RNA exonuclease 2 homolog; RFN; RNA exonuclease 2 homolog; SFN; small fragment nuclease
Description (eCommerce)
REXO2 is a 3'-to-5' exoribonuclease specific for small oligoribonucleotides.It is active on small (primarily </=5 nucleotides in length) single-stranded RNA and DNA oligomers. It may have a role in cellular nucleotide recycling [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y3B8].
Description (Vector)
REXO2 encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process.
Gene ID
25996
Gene Name (eCommerce)
RNA exonuclease 2
Gene Name (Vector)
RNA exonuclease 2
Gene Symbol
REXO2
HGNC ID
HGNC:17851
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
714
Protein Name (eCommerce)
Oligoribonuclease, mitochondrial
RefSeq ID
NM_015523
RefSeq Synonyms
NM_015523, BC143701, BC107887, BC105026, BC105024,
Research Areas
Mitochondrion
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
REXO2 is a 3'-to-5' exoribonuclease specific for small oligoribonucleotides.It is active on small (primarily </=5 nucleotides in length) single-stranded RNA and DNA oligomers. It may have a role in cellular nucleotide recycling [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y3B8].
UniGene ID
Hs.677190
UniProt ID (eCommerce)
Q9Y3B8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.