human PRRG1 Over-expression AAV

Name 
AAV-h-PRRG1
Cat No 
AAV-220000
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PRRG1.

AAV-220000
AAV-h-PRRG1

Ready-to-use AAV expressing Human PRRG1 (proline rich and Gla domain 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PRGP1
Description (Vector)
PRRG1 encodes a vitamin K-dependent, gamma-carboxyglutamic acid (Gla)-containing, single-pass transmembrane protein. This protein contains a Gla domain at the N-terminus, preceded by a propeptide sequence required for post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus is proline-rich containing PPXY and PXXP motifs found in a variety of signaling and cytoskeletal proteins. PRRG1 is highly expressed in the spinal cord. Several alternatively spliced transcript variants have been found for this gene.
Gene ID
5638
Gene Name (Vector)
proline rich and Gla domain 1
Gene Symbol
PRRG1
HGNC ID
HGNC:9469
ORF Size (aa)
657
RefSeq ID
NM_000950
RefSeq Synonyms
NM_001173490, NM_001173489, NM_001173486, NM_001142395, NM_000950, BC060833,
Species
human
UniGene ID
Hs.190341

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.