human PPP1R15B Over-expression AAV

Name
AAV-h-PPP1R15B

Cat No
AAV-219621

Availability
4-5 weeks

This is an AAV expressing Human PPP1R15B.

AAV-219621

AAV-h-PPP1R15B

Ready-to-use AAV expressing Human PPP1R15B (protein phosphatase 1 regulatory subunit 15B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CREP; MSSGM2

Description (Vector)

PPP1R15B promotes dephosphorylation of the transcription initiation factor EIF2-alpha (EIF2S1; MIM 603907) through recruitment of protein phosphatase-1 (PP1) catalytic subunits (see MIM 176875) (Harding et al., 2009 (PubMed 19181853)).(supplied by OMIM, Feb 2010)

Gene ID

84919

Gene Name (Vector)

protein phosphatase 1 regulatory subunit 15B

Gene Symbol

PPP1R15B

HGNC ID

HGNC:14951

ORF Size (aa)

2142

ORF Size (bp)

2142 bp

RefSeq ID

NM_032833

RefSeq Synonyms

NM_032833, BC065280,

Species

human

UniGene ID

Hs.304376

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.