human POLE2 Over-expression AAV

Name 
AAV-h-POLE2
Cat No 
AAV-219360
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human POLE2.

AAV-219360
AAV-h-POLE2

Ready-to-use AAV expressing Human POLE2 (DNA polymerase epsilon 2, accessory subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DNA polymerase epsilon subunit 2; DNA polymerase epsilon subunit B; DNA polymerase II subunit 2; DPE2; polymerase (DNA directed), epsilon 2 (p59 subunit); polymerase (DNA directed), epsilon 2, accessory subunit; polymerase (DNA) epsilon 2, accessory subunit
Description (eCommerce)
DNA Polymerase epsilon Subunit 2 (POLE2) participates in DNA repair and in chromosomal DNA replication [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P56282].
Gene ID
5427
Gene Name (eCommerce)
DNA polymerase epsilon 2, accessory subunit
Gene Name (Vector)
DNA polymerase epsilon 2, accessory subunit
Gene Symbol
POLE2
HGNC ID
HGNC:9178
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1509
ORF Size (bp)
1509 bp
Protein Name (eCommerce)
DNA polymerase epsilon subunit 2
RefSeq ID
NM_002692
RefSeq Synonyms
NM_002692, NM_001197331, NM_001197330, BC126220, BC126218, BC112962,
Research Areas
Cell Cycle,DNA Damage/Repair,Host-Virus Interactions,Telomeric Maintenance
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation,infectious_disease
Species
human
Target Sentence
DNA Polymerase epsilon Subunit 2 (POLE2) participates in DNA repair and in chromosomal DNA replication [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P56282].
UniGene ID
Hs.162777
UniProt ID (eCommerce)
P56282

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.