human PNMT Over-expression AAV

Name 
AAV-h-PNMT
Cat No 
AAV-219306
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PNMT.

AAV-219306
AAV-h-PNMT

Ready-to-use AAV expressing Human PNMT (phenylethanolamine N-methyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PENT; PNMTase
Description (Vector)
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production.
Gene ID
5409
Gene Name (Vector)
phenylethanolamine N-methyltransferase
Gene Symbol
PNMT
HGNC ID
HGNC:9160
ORF Size (aa)
849
RefSeq ID
NM_002686
RefSeq Synonyms
NM_002686, BC037246,
Species
human
UniGene ID
Hs.1892

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.