human PNMT shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PNMT.
shAAV-219306
AAV-h-PNMT-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PNMT (phenylethanolamine N-methyltransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PENT; PNMTase
Description (Vector)
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production.
Gene ID
5409
Gene Name (Vector)
phenylethanolamine N-methyltransferase
Gene Symbol
PNMT
HGNC ID
HGNC:9160
ORF Size (aa)
849
RefSeq ID
NM_002686
RefSeq Synonyms
NM_002686, BC037246,
Species
human
UniGene ID
Hs.1892
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.