human PLEKHM1 Over-expression AAV

Name
AAV-h-PLEKHM1

Cat No
AAV-219197

Availability
4-5 weeks

This is an AAV expressing Human PLEKHM1.

AAV-219197

AAV-h-PLEKHM1

Ready-to-use AAV expressing Human PLEKHM1 (pleckstrin homology and RUN domain containing M1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AP162; B2; OPTB6

Description (Vector)

PLEKHM1 is essential for bone resorption, and may play a critical role in vesicular transport in the osteoclast. Mutations in this gene are associated with autosomal recessive osteopetrosis type 6 (OPTB6). Alternatively spliced transcript variants have been found for this gene.

Gene ID

9842

Gene Name (Vector)

pleckstrin homology and RUN domain containing M1

Gene Symbol

PLEKHM1

HGNC ID

HGNC:29017

ORF Size (aa)

3171

ORF Size (bp)

3171 bp

RefSeq ID

NM_014798

RefSeq Synonyms

NM_014798, BC064361,

Species

human

UniGene ID

Hs.514242

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.